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06-302023

Combination Therapy of PD-1 Inhibitors An…

If Antibody-drug conjugates (ADC) and PD-1 Inhibitors are used in combination, what kind of sparks will be created?

Combination Therapy of PD-1 Inhibitors And Antibody-drug conjugates (ADC)
06-212023

Summary of Treatments for Multiple Myelom…

Currently, there are a variety of drugs available for multiple myeloma, including traditional cytotoxic drugs, immunomodulatory analogs, proteasome inhibitors, antibody-based drugs and CAR T-…

Summary of Treatments for Multiple Myeloma
06-192023

Bispecific Antibody-drug Conjugate Drugs …

In this article, we will introduce the preclinical data of some currently known bispecific ADC drugs in clinical or preclinical.

Bispecific Antibody-drug Conjugate Drugs In Clinical or Preclinical
06-142023

ADCs Targeting the HER Family

Herein, we review the approved and investigational ADCs that target HER family receptors, including EGFR, HER2 and HER3.

ADCs Targeting the HER Family
05-312023

FRα: Another Hot Target In The ADC Field…

FRα will become another hot target in ADC field. As with PD1, once it is successful in one indication, it can be replicated for more indications.

FRα: Another Hot Target In The ADC Field
05-272023

Hypoglycemic & Weight Loss Star Targe…

At present, GLP-1R targeted drugs have occupied half of the field of hypoglycemia and weight loss, while GLP-1R, GCGR, GIPR, FGF21 dual-target and multi-target drugs have also entered the fie…

Hypoglycemic & Weight Loss Star Targets and Representative Drugs
05-242023

Semaglutide: New Therapeutic Potentials

Semaglutide may have the potential to protect against cardiovascular disease, treat NAFLD, fight cancer, alleviate neurodegenerative diseases and reduce addictive behaviors, etc.

Semaglutide: New Therapeutic Potentials
04-252023

Bystander Effects of Antibody-Drug Conjug…

The bystander effect of ADC is expected to solve heterogeneous expression of target antigens (Ag) in metastatic tumor tissues.

Bystander Effects of Antibody-Drug Conjugates
04-232023

List of GLP-1 Receptor Agonists for Diabe…

Glucagon-like peptide-1 (GLP-1), as one of the important targets for the treatment of type 2 diabetes mellitus (T2DM), has obvious therapeutic effect, short half-life and easy to be cleared. …

List of GLP-1 Receptor Agonists for Diabetes & Weight Loss
04-202023

A Comprehensive Guide to ADC Payload Clas…

ADC payloads are critical components of the ADC structure, and their selection and design are crucial for achieving optimal therapeutic efficacy and minimizing toxicity.

A Comprehensive Guide to ADC Payload Classes