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PEGylation

PEGylation is the covalent addition of PEG to one more molecule,most typically peptides, proteins, oligonucleotide, and antibody fragments, that can enhance pharmacologic and pharmaceutical properties of many therapeutics, such as improved drug solubility, reduced dosage frequency with potentially reduced toxicity and without diminished efficacy, extended circulating life, increased drug stability, and enhanced protection from proteolytic degradation, etc.  

Polyethylene glycols (PEGs) are harmless, non-immunogenic, non-antigenic, and highly water soluble and FDA accepted synthetic polymer. It shows a significant role in in biotechnology for drug delivery, cell transfection, and gene editing in non-human cells. A variety of PEGylated drugs are available in the market.

Huateng Pharma, as a leading PEG derivatives sypplier, has over 3,000 high purity PEG linkers kept in stock to empower your PEGylation, bioconjugation, crosslinking for pharmaceutical and biotech R&D, such as PEG Amine, PEG Azide, Maleimide PEG, NHS ester PEG, Thoil PEG and others. We also provide PEGylation services for your reference. 

PEGylation reagents with molecular weights and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at sales@huatengusa.com about pricing and availability.

Featured PEGylation Reagents

PEG Derivatives for PEGylated Proteins

Catalog No.

Name

Structure

 Purity 

10003

mPEG-Aldehyde

mPEG-CHO.gif≥95%

10023

mPEG-Mal

mPEG-Mal.gif≥95%

10024

mPEG-SC

mPEG-SC.gif≥95%

 10026

mPEG-SPA

mPEG-SPA.gif≥95%


PEG Derivatives for PEGylated Peptide

Catalog No.

Name

Structure

 Purity 

10729

NH2-PEG2-CH2CH2COOtBu

NH2-PEG2-CH2CH2COOtBu.gif≥95%

10818

Fmoc-NH-PEG6-COOH

Fmoc-NH-PEG6-COOH.gif≥95%

10823

Fmoc-NH-PEG4-CH2COOH

Fmoc-NH-PEG4-CH2COOH.gif≥95%

11607

Boc-NH-PEG3-CH2COOH

Boc-NH-PEG3-CH2COOH.gif≥95%

 10852

Boc-NH-PEG2-CH2COOH

Boc-NH-PEG2-CH2COOH.gif≥95%

more-peg-products.jpg